The effectiveness of single-dose oral AZITHROMYCIN in cystic fibrosis, also for its anti-inflamjatory properties. Our study reveals that doxycycline and cotrimoxazole are the cheapest drugs to use. By using sulfobromophthalein (bsp) and the hmg-coa reductase inhibitor pravastatin as substrates, the effects of the macrolides azithromycin, clarithromycin, erythromycin, and roxithromycin and of the ketolide telithromycin on the oatp1b1- and oatp1b3-mediated uptake were analyzed. Azithromycin may enhance the anti-blood-clotting effects of warfarin and possibly other anticoagulant medicines.
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